The effect of SphK1/S1P signaling pathway on hepatic sinus microcirculation in rats with hepatic ischemia-reperfusion injury

• 作者: Li-Ming Jin Yuan-Xing Liu Jian Cheng Lin Zhou Hai-Yang Xie Xiao-Wen Feng Hui Li Yan Shen Xiao Xu Shu-Sen Zheng
• 来源期刊: 国际肝胆胰疾病杂志（英文版）
• 年，卷（期）: 2022,（1）
• 所属期刊栏目: LETTERS TO THE EDITOR
• 页码范围: 94-98
• 页数: 5页
• 语种: 英文

摘要

To the Editor: Hepatic ischemia-reperfusion (I/R) injury is the component of liver injury related to liver transplantation and liver surgery [ 1–3 ]. The hepatic sinus microcirculation injury is a central part of hepatic I/R injury, which eventually leads to hepatocyte injury. This process is closely associated with the participation of liver nonparenchymal cells such as Kuffer cells, hepatic stellate cells, liver sinusoidal endothelial cells (LSECs), and cytokines.