Intestinal pseudo-obstruction in inactive systemic lupus erythematosus: An unusual finding

• 作者: Angelo Ricchiuti Francesco Costa Giulia Leonardi Maria Gloria Mumolo Massimo Bellini Nicola de Bortoli Santino Marchi Stefano Bombardieri
• 来源期刊: 世界胃肠药理与治疗学杂志：英文版（电子版）
• 学科: 医学
• 关键词: Chronic INTESTINAL PSEUDO-OBSTRUCTION SYSTEMIC LUPUS ERYTHEMATOSUS
• 年，卷（期）: 2010,（6）
• 页码范围: 135-136
• 页数: 2页
• 分类号: R593.241

摘要

Chronic intestinal pseudo-obstruction (CIP) is an infre-quent complication of an active systemic lupus erythema-tosus (SLE). We illustrate a case of SLE inactive-related CIP. A 51-year old female with inactive SLE (ECLAM score 2) was hospitalized with postprandial fullness, vomiting, abdominal bloating and abdominal pain. She had had no bowel movements for five days. Plain abdominal X-ray revealed multiple fluid levels and dilated small and large bowel loops with air-fluid levels. Intestinal contrast radiology detected dilated loops. CIP was diagnosed. The patient was treated with prokinetics, octreotide, claritromycin, rifaximin, azathioprine and tegaserod without any clinical improvement. Then methylprednisolone (500 mg iv daily) was started. After the first administration, the patient showed peristaltic movements. A bowel movement was reported after the second administration. A plain abdominal X-ray revealed no air-fluid levels. Steroid therapy was slowly reduced with complete resolution of the symptoms. The patient is still in a good clinical condition. SLE-related CIP is generally reported as a complication of an active disease. In our case, CIP was the only clinical demonstration of the SLE.