Engineered magnetic core shell nanoprobes:Synthesis and applications to cancer imaging and therapeutics

• 作者: Keya Chaudhuri Samir Mandal
• 来源期刊: 世界生物化学杂志：英文版（电子版）
• 学科: 医学
• 关键词: MAGNETIC core shell nanoparticles MAGNETIC resonance imaging Cancer THERAPEUTICS Drug delivery HYPERTHERMIA
• 年，卷（期）: 2016,（1）
• 页码范围: 158-167
• 页数: 10页
• 分类号: R730.5

摘要

Magnetic core shell nanoparticles are composed of a highly magnetic core material surrounded by a thin shell of desired drug, polymer or metal oxide. These magnetic core shell nanoparticles have a wide range of applications in biomedical research, more specifically in tissue imaging, drug delivery and therapeutics. The present review discusses the up-to-date knowledge on the various procedures for synthesis of magnetic core shell nanoparticles along with their applications in cancer imaging, drug delivery and hyperthermia or cancer therapeutics. Literature in this area shows that magnetic core shell nanoparticle-based imaging, drug targeting and therapy through hyperthermia can potentially be a powerful tool for the advanced diagnosis and treatment of various cancers.