Unusual presentation of Erdheim-Chester disease in a child with acute lymphoblastic leukemia

• 作者: Archana George Vallonthaiel Asit Ranjan Mridha Manisha Jana Mehar Chand Sharma Sameer Bakhshi Shah Alam Khan Shivanand Gamanagatti
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: Erdheim-Chester disease OSTEOLYTIC LESION BONE Acute LYMPHOBLASTIC LEUKEMIA
• 年，卷（期）: 2016,（8）
• 页码范围: 757-763
• 页数: 7页
• 分类号: R733.71

摘要

Erdheim-Chester disease(ECD) is an uncommon, nonfamilial, non-Langerhans cell histiocytosis, which involves skeletal system and soft tissue usually in middle aged and elderly patients. The characteristic radiologic features include bilateral, symmetric cortical osteosclerosis of the diaphyseal and metaphyseal parts of the long bones, or bilateral symmetrically abnormal intense 99 mTechnetium labelling of the metaphyseal-diaphyseal region of the long bones, and computed tomography scan findings of 'coated aorta' or 'hairy kidneys'. ECD in childhood with osteolytic lesion is extremely rare. We describe an unusual case with an expansile lytic bone lesion at presentation in a case of acute lymphoblastic leukemia.