Synthesis and Spectral Characterization of Novel 2-Pyrazoline and Bis-2-Pyrazoline Containing Quinoline Moiety

• 作者: Abdelmalek Bouraiou Allaoua Kedjadja Rachid Merdes
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: PYRAZOLINE CHALCONE QUINOLINE CYCLOCONDENSATION
• 年，卷（期）: yjhxgjqkyw_2018,（1）
• 页码范围: 105-114
• 页数: 10页
• 分类号: O6

摘要

Eight new compounds containing in their structures substituted quinoline and pyrazole entity were synthesized in good to excellent yield by cyclocondensation reaction of chalcones and hydrazine hydrate. This reaction was conducted in formic acid in presence of BF3·Et2O or in acetic acid. These approaches were extended to bis-chalcones, which delivered functionalized bispyrazolines. The structures of the prepared compounds were confirmed by IR, 1HNMR, 13CNMR and mass spectral analysis.