Role of narrow band ultra violet radiation as an add-on therapy in peritoneal dialysis patients with refractory uremic pruritus

• 作者: Rajesh Waikhom Ranjeeta Sapam
• 来源期刊: 世界肾病学杂志：英文版
• 学科: 医学
• 关键词: Narrow band ultraviolet RADIATION UREMIC PRURITUS PERITONEAL DIALYSIS visual analogue score RETROSPECTIVE study
• 年，卷（期）: 2018,（4）
• 页码范围: 84-89
• 页数: 6页
• 分类号: R

摘要

AIM To assess the role of narrow band ultraviolet B(UVB)as a treatment option in peritoneal dialysis patients with refractory uremic pruritus.METHODS In this retrospective study,29 adult patients with end stage renal failure on peritoneal dialysis,and who had refractory uremic pruritus,were given narrow band UVB radiation as an add-on therapy to standard care for a duration of 12 wk.The response to the pruritus was assessed both weekly and at the end of the study period using a visual analogue score(VAS).RESULTS The average VAS score at the end of the study was 3.14±1.59,which was significant compared to the baseline value of 7.75±1.02(P<0.05).Improvements in symptoms were noted in 19 out of 21(90.4%)patients.However,relapse occurred in six out of the 19 patients who responded.The dropout rate was high during the study period(33.3%).CONCLUSION Narrow band UVB is effective as an add-on therapy in peritoneal dialysis patients with refractory uremic pruritus.However,the present regime is cumbersome and patient compliance is poor.