Unconventional secretion: cargo channeling by TMED10

• 作者: Jayanta Debnath Tan A.Nguyen
• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2020,（9）
• 所属期刊栏目: RESEARCH HIGHLIGHTS
• 页码范围: 713-714
• 页数: 2页
• 语种: 英文

摘要

Cytosolic proteins lacking a signal peptide are often loaded into vesicles and secreted via unconventional protein secretion pathways.A recent paper in Cell identifies the transmembrane protein TMED10 as a protein channel for the vesicular translocation and secretion of mature IL-1β and other leaderless cargoes.