Epidermal restriction confers robustness to organ shapes

• 作者: Fei Du Jinrong Hu Lüwen Zhou Mian Long Shiliang Feng Shouqin Lü Yuling Jiao
• 来源期刊: 植物学报（英文版）
• 年，卷（期）: 2020,（12）
• 所属期刊栏目: Cell and Developmental Biology
• 页码范围: 1853-1867
• 页数: 15页
• 语种: 英文
• DOI: 10.1111/jipb.12998

摘要

The shape of comparable tissues and organs is consistent among individuals of a given species, but how this consistency or robustness is achieved remains an open question. The interaction between morphogenetic factors determines organ formation and subsequent shaping, which is ultimately a mechanical process. Using a computational approach, we show that the epidermal layer is essential for the robustness of organ geometry control. Specifically, proper epidermal restriction allows organ asymmetry maintenance, and the tensile epi-dermal layer is sufficient to suppress local variability in growth, leading to shape robustness. The model explains the enhanced organ shape variations in epidermal mu-tant plants. In addition, differences in the patterns of epidermal restriction may underlie the initial establish-ment of organ asymmetry. Our results show that epi-dermal restriction can answer the longstanding question of how cellular growth noise is averaged to produce precise organ shapes, and the findings also shed light on organ asymmetry establishment.