药学学报(英文版)2022年出版文献-钛学术文献服务平台

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药学学报(英文版)

投稿

Acta Pharmaceutica Sinica B

CSTPCD

影响因子 1.2053

ISSN：

2211-3835

CN：

10-1171/R

出版周期：

双月刊

邮编：

100050

地址：

北京市先农坛街1号

出版文献量（篇）

688

总下载数（次）

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热门刊内文献

年度刊次

1. Mitochondrial complex Ⅰ as a therapeutic target for Alzheimer's disease

作者： Eugenia Trushina Sergey Trushin Md Fayad Hasan

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 483-495

摘要： Alzheimer's disease(AD),the most prominent form of dementia in the elderly,has no cure.Strategi...
2. Apolipoprotein E and Alzheimer's disease

作者： Benjamin R.Troutwine Laylan Hamid Colton R.Lysaker Taylor A.Strope Heather M.Wilkins

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 496-510

摘要： Genetic variation in apolipoprotein E(APOE)influences Alzheimer's disease(AD)risk.APOE e4 allel...
3. Targeting whole body metabolism and mitochondrial bioenergetics in the drug development for Alzheimer's disease

作者： Steven N.Austad Scott Ballinger Thomas W.Buford Christy S.Carter Daniel L.Smith Jr Victor Darley-Usmar Jianhua Zhang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 511-531

摘要： Aging is by far the most prominent risk factor for Alzheimer's disease(AD),and both aging and A...
4. Repurposing non-oncology small-molecule drugs to improve cancer therapy:Current situation and future directions

作者： Leilei Fu Wenke Jin Jiahui Zhang Lingjuan Zhu Jia Lu Yongqi Zhen Lan Zhang Liang Ouyang Bo Liu Haiyang Yu

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 532-557

摘要： Drug repurposing or repositioning has been well-known to refer to the therapeutic applications ...
5. Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma

作者： Danyu Du Chan Liu Mengyao Qin Xiao Zhang Tao Xi Shengtao Yuan Haiping Hao Jing Xiong

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 558-580

摘要： Hepatocellular carcinoma(HCC)is an aggressive human cancer with increasing incidence worldwide....
6. Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors

作者： Shenghua Gao Tianguang Huang Letian Song Shujing Xu Ysen Cheng Srinivasulu Cherukupalli Dongwei Kang Tong Zhao Lin Sun Jian Zhang Peng Zhan Xinyong Liu

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 581-599

摘要： Novel therapies are urgently needed to improve global treatment of SARS-CoV-2 infection.Herein,...
7. Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome

作者： Makhloufi Zoulikha Qingqing Xiao George Frimpong Boafo Marwa A.Sallam Zhongjian Chen Wei He

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 600-620

摘要： The use of small interfering RNAs(siRNAs)has been under investigation for the treatment of seve...
8. Fighting type 2 diabetes:Formulation strategies for peptide-based therapeutics

作者： Carlos Bendicho-Lavilla Iria Seoane-Via?o Francisco J.Otero-Espinar Asteria Luzardo-álvarez

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 621-636

摘要： Diabetes mellitus is a major health problem with increasing prevalence at a global level.The di...
9. Modulating effects of RAMPs on signaling profiles of the glucagon receptor family

作者： Lijun Shao Yan Chen Shikai Zhang Zhihui Zhang Yongbing Cao Dehua Yang Ming-Wei Wang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 637-650

摘要： Receptor activity-modulating proteins(RAMPs)are accessory molecules that form com-plexes with s...
10. IKKβ mediates homeostatic function in inflammation via competitively phosphorylating AMPK and IκBα

作者： Juan Liu Yuxin Zhuang Jianlin Wu Qiang Wu Meixian Liu Yue Zhao Zhongqiu Liu Caiyan Wang Linlin Lu Yingjiao Meng Kawai Lei Xiaojuan Li Qibiao Wu Elaine Lai-Han Leung Zhengyang Guo Liang Liu Ting Li

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 651-664

摘要： Inhibitor of nuclear factor kappa-B kinase subunit beta(IKKβ)is one of important kinases in inf...
11. Anti-aging effects of chlorpropamide depend on mitochondrial complex-Ⅱ and the production of mitochondrial reactive oxygen species

作者： Zhifan Mao Wenwen Liu Yunyuan Huang Tianyue Sun Keting Bao Jiali Feng Alexey Moskalev Zelan Hu Jian Li

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 665-677

摘要： Sulfonylureas are widely used oral anti-diabetic drugs.However,its long-term usage effects on p...
12. Aging-elevated inflammation promotes DNMT3A R878H-driven clonal hematopoiesis

作者： Min Liao Ruiqing Chen Yang Yang Hanqing He Liqian Xu Yuxuan Jiang Zhenxing Guo Wei He Hong Jiang Jianwei Wang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 678-691

摘要： Aging-elevated DNMT3A R882H-driven clonal hematopoiesis(CH)is a risk factor for myeloid maligna...
13. Abrogation of HnRNP L enhances anti-PD-1 therapy efficacy via diminishing PD-L1 and promoting CD8+T cell-mediated ferroptosis in castration-resistant prostate cancer

作者： Xumin Zhou Libin Zou Hangyu Liao Junqi Luo Taowei Yang Jun Wu Wenbin Chen Kaihui Wu Shengren Cen Daojun Lv Fangpeng Shu Yu Yang Chun Li Bingkun Li Xiangming Mao

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 692-707

摘要： Owing to incurable castration-resistant prostate cancer(CRPC)ultimately developing after treati...
14. Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways

作者： Xiang Wang Xinxin Chen Wenqian Zhou Hongbo Men Terigen Bao Yike Sun Quanwei Wang Yi Tan Bradley B.Keller Qian Tong Yang Zheng Lu Cai

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 708-722

摘要： Herein,we define the role of ferroptosis in the pathogenesis of diabetic cardiomyopathy(DCM)by ...
15. Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus

作者： Hang Qi Yuntao Shi Han Wu Canyang Niu Xiaoying Sun KeWei Wang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 723-734

摘要： Genetic gain-of-function mutations of warm temperature-sensitive transient receptor poten-tial ...
16. The cell cycle inhibitor P21 promotes the development of pulmonary fibrosis by suppressing lung alveolar regeneration

作者： Xiaoxi Lv Chang Liu Shanshan Liu Yunxuan Li Wanyu Wang Ke Li Fang Hua Bing Cui Xiaowei Zhang Jiaojiao Yu Jinmei Yu ZhuoWei Hu

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 735-746

摘要： The cell cycle inhibitor P21 has been implicated in cell senescence and plays an important role...
17. Ample dietary fat reduced the risk of primary vesical calculi by inducing macrophages to engulf budding crystals in mice

作者： Huiling Chen Kaiqiang Hu Yaru Liang Yuqi Gao Chenye Zeng Kang Xu Xiaojin Shi Liyuan Li Yuemiao Yin Yi Qiao Ying Qiu Qingfei Liu Zhao Wang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 747-758

摘要： Although primary vesical calculi is an ancient disease,the mechanism of calculi formation remai...
18. Targeting glutamine utilization to block metabolic adaptation of tumor cells under the stress of carboxyamidotriazole-induced nutrients unavailability

作者： Jing Shi Rui Ju Hongting Gao Yuqing Huang Lei Guo Dechang Zhang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 759-773

摘要： Tumor cells have unique metabolic programming that is biologically distinct from that of corres...
19. A novel PI3K inhibitor XH30 suppresses orthotopic glioblastoma and brain metastasis in mice models

作者： Ming Ji Dongjie Wang Songwen Lin Chunyang Wang Ling Li Zhihui Zhang Jing Jin Deyu Wu Yi Dong Heng Xu Duo Lu Xiaoguang Chen

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 774-786

摘要： Glioblastoma is carcinogenesis of glial cells in central nervous system and has the highest inc...
20. TGR5 deficiency activates antitumor immunity in non-small cell lung cancer via restraining M2 macrophage polarization

作者： Lifang Zhao Hongyan Zhang Xueqing Liu Shan Xue Dongfang Chen Jing Zou Handong Jiang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 787-800

摘要： The bile acid-responsive G-protein-coupled receptor TGR5 is expressed in monocytes and macropha...
21. Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut microbiome using genetically modified mice

作者： Mallory Little Moumita Dutta Hao Li Adam Matson Xiaojian Shi Gabby Mascarinas Bruk Molla Kris Weigel Haiwei Gu Sridhar Mani Julia Yue Cui

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 801-820

摘要： Pharmacological activation of the xenobiotic-sensing nuclear receptors pregnane X receptor(PXR)...
22. miR-7/TGF-β2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis

作者： Tao Su Suchao Huang Yanmin Zhang Yajuan Guo Shuwei Zhang Jiaji Guan Mingjing Meng Linxin Liu Caiyan Wang Dihua Yu Hiu-Yee Kwan Zhiying Huang Qiuju Huang Elaine Lai-Han Leung Ming Hu Ying Wang Zhongqiu Liu Linlin Lu

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 821-837

摘要： Acidosis,regardless of hypoxia involvement,is recognized as a chronic and harsh tumor microenvi...
23. Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

作者： Xin Sun Yuhan Shu Guiqin Ye Caixia Wu Mengting Xu Ruilan Gao Dongsheng Huang Jianbin Zhang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 838-852

摘要： Parkin,an E3 ubiquitin ligase,plays a role in maintaining mitochondrial homeostasis through tar...
24. A novel inhibitor of N6-methyladenosine demethylase FTO induces mRNA methylation and shows anti-cancer activities

作者： Guoyou Xie Xu-Nian Wu Yuyi Ling Yalan Rui Deyan Wu Jiawang Zhou Jiexin Li Shuibin Lin Qin Peng Zigang Li Hongsheng Wang Hai-Bin Luo

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 853-866

摘要： N6-methyladenosine(m6A)modification is critical for mRNA splicing,nuclear export,stabil-ity and...
25. Preclinical evaluation and pilot clinical study of[18F]AlF-labeled FAPI-tracer for PET imaging of cancer associated fibroblasts

作者： Kongzhen Hu Junqi Li Lijuan Wang Yong Huang Li Li Shimin Ye Yanjiang Han Shun Huang Hubing Wu Jin Su Ganghua Tang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 867-875

摘要： In recent years,fibroblast activation protein(FAP)has emerged as an attractive target for the d...
26. Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells

作者： Qiufen Zhang Yingyi Chen Duan Ni Zhimin Huang Jiacheng Wei Li Feng Jun-Cheng Su Yingqing Wei Shaobo Ning Xiuyan Yang Mingzhu Zhao Yuran Qiu Kun Song Zhengtian Yu Jianrong Xu Xinyi Li Houwen Lin Shaoyong Lu Jian Zhang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 876-889

摘要： SIRT6 belongs to the conserved NAD+-dependent deacetylase superfamily and mediates multiple bio...
27. Antrodia cinnamomea exerts an anti-hepatoma effect by targeting PI3K/AKT-mediated cell cycle progression in vitro and in vivo

作者： Yan Zhang Pin Lv Junmei Ma Ning Chen Huishan Guo Yan Chen Xiaoruo Gan Rong Wang Xuqiang Liu Sufang Fan Bin Cong Wenyi Kang

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 890-906

摘要： Antrodia cinnamomea is extensively used as a traditional medicine to prevention and treat-ment ...
28. Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation

作者： Qiubing Chen Qian Li Yuqi Liang Menghang Zu Nanxi Chen Brandon S.B.Canup Liyong Luo Chenhui Wang Liang Zeng Bo Xiao

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 907-923

摘要： Although several artificial nanotherapeutics have been approved for practical treatment of meta...
29. Enhanced tumor homing of pathogen-mimicking liposomes driven by R848 stimulation:A new platform for synergistic oncology therapy

作者： Xiaobei Cheng Pei Yu Xiang Zhou Jiale Zhu Yubao Han Chao Zhang Lingyi Kong

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 924-938

摘要： Although multifarious tumor-targeting modifications of nanoparticulate systems have been at-tem...
30. Inhibiting collagen I production and tumor cell colonization in the lung via miR-29a-3p loading of exosome-/liposome-based nanovesicles

作者： Yan Yan Cancan Du Xixi Duan Xiaohan Yao Jiajia Wan Ziming Jiang Zhongyu Qin Wenqing Li Longze Pan Zhuoyu Gu Fazhan Wang Ming Wang Zhihai Qin

刊名：药学学报(英文版)

发表期刊： 2022年2期

页码: 939-951

摘要： The lung is one of the most common sites for cancer metastasis.Collagens in the lung pro-vide a...

药学学报(英文版)基本信息

刊名	药学学报(英文版)	主编
曾用名
主办单位		主管单位
出版周期	双月刊	语种	eng
ISSN	2211-3835	CN	10-1171/R
邮编	100050	电子邮箱	yxxb@imm.ac.cn
电话	010-63026192	网址
地址	北京市先农坛街1号