<正>In this paper,by using the fixed-point index theory,we study the existence of sign-changing solution to some three-point boundary value problem {y″(t)+f(y)=0,t∈[0,1], y(0)=0,y′(1)=αy′(η), where 0<α<1,0<η<1,f:R→R is continuous,strictly increasing and f(0)=0.