The sandwich structure is of great interest because of its advantage of combining light weight and high flexural stiffness. Many previous researchers have studied the failure modes in sandwich structures and the effects on the load capacity caused by the change of the constituent materials’ properties. In this research, by applying Finite Element Analysis (FEA) method, we simulated a cantilever beam composed of a sandwich structure in Abaqus, to find out the preferred design principles that help decrease the stress and displacement in the beam when applied a uniform load. We also determined the effect of the core geometry on decreasing the displacement and the stress in the beam.