Recent advances in the synthesis of 1,1-diarylalkanes by transition-metal catalysis

• 作者: Md.Belal Zheqi Li Xiuqiang Lu Guoyin Yin
• 来源期刊: 中国科学：化学（英文版）
• 年，卷（期）: 2021,（4）
• 所属期刊栏目: REVIEWS
• 页码范围: 513-533
• 页数: 21页
• 语种: 英文

摘要

1,1-Diaryl moieties are core structures in a wide range of bioactive and pharmaceutical compounds.Transition-metal catalysis is a convenient approach to accessing these invaluable compounds affording high yields and enantioselectivities.This review summarizes 1,1-diarylalkanes synthesis through transition metal catalysis.Particular focus is given to recent developments,such as reductive cross-electrophile couplings,benzylic C-H bond arylation,transformations involving metal migration,asymmetric hydrogenation of 1,1-diarylalkenes and three-component coupling reactions.