The gate to metabolic crossroads

• 作者: Haiquan Wang Chaojun Li
• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2021,（15）
• 所属期刊栏目: RESEARCH HIGHLIGHTS
• 页码范围: 1488-1490
• 页数: 3页
• 语种: 英文

摘要

Glycerol is a simple polyhydroxy-three-carbon compound that is highly hydrophilic and is considered a central intermediate metabolite for cellular metabolism.It is found at the crossroads among several metabolic pathways,such as glycolysis and gluco-neogenesis(for carbohydrates),lipogenesis,lipolysis,and glycero-neogenesis(for lipids),pentose-phosphate pathway(for nucleic acids),amino acid synthesis,and even energy generation by oxida-tive phosphorylation[1](Fig.1).