Rejuvenation of Ovary and Thin Endometrium by Autologous PRP Injection in POR and Recurrent Implantation Failure

• 作者: Yazhini Selvaraj Kanchana Malaisamy
• 来源期刊: 性医学进展(英文)
• 学科: 医学
• 关键词: Platelet Rich Plasma (PRP) Poor Ovarian Reserve (POR) Premature Ovarian Insufficiency (POI) Anti Mullerian Hormone (AMH) Antral Follicle Counts (AFC) Intra Cytoplasmic Sperm Injection (ICSI) Outpatient Procedure (OP)
• 年，卷（期）: 2021,（1）
• 页码范围: 1-15
• 页数: 15页
• 分类号: R71

摘要

In India</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> the problem of infertility is growing and in the last 5 years</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> it has gone up to 20%</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">30%. This ongoing prospective clinical study brings forth a novel, innovative, effective, simple, affordable, easily performed outpatient procedure (OP) and a promising therapeutic method in rejuvenating the Ageing Ovaries and Thin Endometrium, with autologous Platelet Rich Plasma (PRP). This clinical study proves to give a better result in rejuvenating Ovary and treating the Thin Endometrium. This pilot study include</span><span style="font-family:Verdana;">d</span><span style="font-family:Verdana;"> five women (28</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">44 years) with Poor Ovarian Response (POR), Premature Ovarian Insufficiency (POI) and Perimenopause and Thirty-nine women (22</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">43</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">years.) with recurrent implantation failure due to Thin Endometrium were subjected to autologous PRP instillation under Ultrasound Guidance, and Hysteroscopic guided PRP. After PRP</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> a significant output was obtained, with improved Anti Mullerian Hormone (AMH) and Antral Follicle Count (AFC) and out of five women three women conceived by Intra Cytoplasmic Sperm Injection (ICSI). PRP injected in wom