Drosophila Ortholog of Mammalian Immediate-Early Gene Npas4 is Specifically Responsive to Reversal Learning
Drosophila Ortholog of Mammalian Immediate-Early Gene Npas4 is Specifically Responsive to Reversal Learning
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摘要:
Dear Editor,
In dynamic environments,the memory system of the brain must be able to perceive and process conflicting experi-ences to reach an adaptive decision.In Drosophila,in contrast to consistent experiences,conflicting experiences trigger significantly increased Racl activity which medi-ates active forgetting[1].The ability to cope with conflicting experiences but not simple learning experiences is impaired in mutants of multiple autism-risk genes[2].