<正>In this paper, when μ< 1/4, and 2 <q<2(3-σ),0≤<σ≤ 2 we discuss the existence of the solution for a nonlinear elliptic equation by an improved Sobolev-Hardy inequality. We also proved that the constant is optimal in the improved Sobolev-Hardy inequality. We also prove that the problem has no nontrivial solution when |y|<R,μ>0 and q=2(3-σ),the method is coming from the idea of Pohozaev.